Dr Masenya became the youngest medical doctor in South Africa in 1999 at the age of 20. He went on to specialise in the field of Histopathology before joining Lancet Laboratories in 2006, where he currently serves as a partner. In 2020, he was appointed as a Board Member to oversee Employment Equity. He has continued to teach Dermatopathology at UKZN medical school as an honorary lecturer. He received his Executive MBA from Henley in 2018.